Cyclooxygenase-2 expression in cervical cancer
نویسندگان
چکیده
منابع مشابه
Cyclooxygenase-2 expression in cervical cancer.
BACKGROUND/AIM Cyclooxygenase (COX) or prostaglandin H2 synthase is the first enzyme that catalyzes the first two steps in the biosynthesis of prostaglandins from arachidonic acid. The aim of the study was to determine the expression level of COX-2 in patients with cervical cancer and compare it with that in the control group with no cervical pathology. METHODS The study included 76 patients ...
متن کاملRole of cyclooxygenase-2 in cervical cancer
Concurrent radiation and chemotherapy is a standard treatment of patients with cervical cancer in FIGO stages IB2-IVA. Chemotherapy given in the same time as irradiation improved survival significant, but not involves all patients. Cancer recurrence is the most common treatment failure in patients with advanced tumor. Further improvement in the treatment of advanced cases is essential. The incr...
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Background/Aim. Cyclooxygenase (COX) or prostaglandin H2 synthase is the first enzyme that catalyzes the first two steps in the biosynthesis of prostaglandins from arachidonic acid. The aim of the study was to determine the expression level of COX-2 in patients with cervical cancer and compare it with that in the control group with no cervical pathology. Methods. The study included 76 patients ...
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Introduction: cyclooxygenase-2 (COX-2) is involved in pathogenesis of various tumors and possibly malignant skin tumors including malignant melanoma; however, there is not enough information about COX-2 expression in benign melanocytic lesions. In the present study we compared the expression levels of COX-2 in malignant melanoma and benign melanocytic lesions. Method: In this analytical study, ...
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Multiple lines of evidence suggest that cyclooxygenase-2 (COX-2) is an important target for preventing epithelial malignancies. Little is known, however, about the expression of COX-2 in gynecological malignancies. By immunoblot analysis, COX-2 was detected in 12 of 13 cases of cervical cancer but was undetectable in normal cervical tissue. Immunohistochemistry revealed COX-2 in malignant epith...
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ژورنال
عنوان ژورنال: Military Medical and Pharmaceutical Journal of Serbia
سال: 2014
ISSN: 0042-8450,2406-0720
DOI: 10.2298/vsp1411997m